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ジャンクDNAの一部はゲノムの句読点か'Junk' DNA May Be The 'Punctuation' Of The Genome
http://www.medicalnewstoday.com/articles/76763.php
マウスのゲノムでSINE B2という名称の綴りが成長ホルモン生成に関わる遺伝子の中にあるが、その位置はfunctional domain boundariesの形成に極めて重要であることが判明した。
'Junk' DNA May Be The 'Punctuation' Of The GenomeGenes, which make up about four percent of the genome, encode for proteins, 'the building blocks of life.' An international collaboration of scientists led by Michael G. Rosenfeld, M.D., Howard Hughes Medical Investigator and UCSD professor of medicine, found that some of the remaining 96 percent of genomic material might be important in the formation of boundaries that help properly organize these building blocks.
The researchers' data suggest that repeated genomic sequences might be a widely used strategy used in mammals to organize functional domains.
The research team studied a repeated genomic sequence called SINE B2, which is located on the growth hormone gene locus, the gene related to the aging process and longevity. The scientists were surprised to find that SINE B2 sequence is critical to formation of the functional domain boundaries for this locus.
マウスのゲノムでSINE B2という名称の綴りが成長ホルモン生成に関わる遺伝子の中にあるが、その位置はfunctional domain boundariesの形成に極めて重要であることが判明した。
'Junk' DNA May Be The 'Punctuation' Of The GenomeGenes, which make up about four percent of the genome, encode for proteins, 'the building blocks of life.' An international collaboration of scientists led by Michael G. Rosenfeld, M.D., Howard Hughes Medical Investigator and UCSD professor of medicine, found that some of the remaining 96 percent of genomic material might be important in the formation of boundaries that help properly organize these building blocks.
The researchers' data suggest that repeated genomic sequences might be a widely used strategy used in mammals to organize functional domains.
The research team studied a repeated genomic sequence called SINE B2, which is located on the growth hormone gene locus, the gene related to the aging process and longevity. The scientists were surprised to find that SINE B2 sequence is critical to formation of the functional domain boundaries for this locus.
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Latest page update: made by ishida
, Jul 18 2007, 10:29 AM EDT
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Keyword tags:
boundary elements
functional domains
genes
Genome
Junk DNA
non-coding sequences
punctuation
punctuation mark
repeated genomic sequences
repetitive
SINE B2
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