http://www.scienceahead.com/entry/new-synthetic-3d-scaffold-may-replace-petri-dish-for-growing-cells/

http://www.medgadget.com/archives/2006/12/3d_stem_cell_cu.html

合成３次元の足場scaffoldを使って細胞培養。ペトリ皿の代替となるか？New Synthetic 3D Scaffold May Replace Petri Dish for Growing Cells!

Irani Irani,New Delhi, INDIA
Dec 28 2006, 6:44 am GMT

この足場scaffoldはタンパク質ナノファイバー製。各ナノファイバーは髪の毛の5000分の１で、針の穴の20000分の１。
この実験では成長したマウスの健全な幹細胞のコロニー生育に成功。これは３次元の足場上に細胞を成長させ、これは２次元システムの欠点を持たない。
これは体内での細胞の成長のより正確な理解に役立つだけでなく、組織細胞培養と再生医療に必要な組織、すなわち、皮膚の接ぎ木graftsまたは神経細胞といったものに必要なミクロの環境を提供することができると思われる。これらは、怪我または病気で失われた脳細胞の代替に使用される。
マイナスの影響が皆無であり、この足場そのものを直接体内に移植可能であると言う。

An MIT engineer and his Italian colleagues have successfully invention a 3D scaffold that in a near future may replace the ubiquitous Petri dish for growing cells! A designer scaffold is developed from a network of protein nanofibers. Each nano-fiber is 5,000 times thinner compared to a human hair and contains pores up to 20,000 times smaller than the eye of a needle!
The researchers have successfully grown a healthy colony of stem cells of an adult mouse. They have grown the cells on the three-dimensional scaffold, which does not have the two-dimensional systems’ drawbacks.
This invention of the new synthetic structure does not only help researchers build a more accurate picture of how cells grow and behave in the body. It can also provide a more conducive microenvironment required for the tissue cell cultures and tissues that are used in regenerative medicine — like skin grafts or neurons. These are used to replace brain cells lost to injury or disease.
With no ill effects, the scaffold itself can be transplanted directly into the body!

Tags: synthetic 3D scaffold, petri dish, growing cells, protein nanofibers